Polyethylene Glycol

Polyethylene Glycol

Drug monograph · NCLEX study reference
Trade names	MiraLAX
Therapeutic class	Laxative
Pharmacologic class	Osmotic laxative
Onset / peak / duration	Onset 1 to 3 days.
Half-life / level	Minimal absorption.
Routes	PO (oral)
High-alert (ISMP)	No
Black box warning	None
Antidote / reversal	Not applicable.
Pregnancy / lactation	Commonly used.

Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.

Polyethylene Glycol (brand name MiraLAX) — Laxative; Osmotic laxative.

Identification

• Therapeutic class: Laxative.
• Pharmacologic class: Osmotic laxative.

Pharmacology

• Mechanism of action: Holds water in the stool to promote a bowel movement.
• Onset / peak / duration: Onset 1 to 3 days.
• Half-life / therapeutic level: Minimal absorption.

Clinical use

• Indications: Occasional constipation, bowel cleansing (high-volume forms).
• Usual dose, route, frequency: 17 g PO in 8 ounces of liquid once daily.
• Maximum dose / adjustments: Short-term use unless directed.

Safety

• Contraindications: Bowel obstruction.
• Black box warning: None.
• Interactions: Minimal.
• Pregnancy / lactation: Commonly used.
• High-alert: No.

Adverse effects

• Common side effects: Bloating, cramping, loose stools.
• Serious effects to report: Severe diarrhea, electrolyte disturbance with overuse.
• Antidote / reversal: Not applicable.

Nursing process

• Assessment before administration: Bowel pattern, hydration.
• Interventions during therapy: Dissolve fully in liquid.
• Monitor: Bowel movements, electrolytes with prolonged use.
• Evaluation / expected outcome: Regular bowel movements.

Patient teaching

• Patient teaching: Mix in a beverage; effect takes a day or more.
• Notify provider if: No relief in a week, severe diarrhea.
• Administration tips: Dissolve in 8 ounces of liquid.