Prednisolone
(Redirected from Orapred)
| Drug monograph · NCLEX study reference | |
| Trade names | Prelone, Orapred |
|---|---|
| Therapeutic class | Anti-inflammatory, immunosuppressant |
| Pharmacologic class | Systemic corticosteroid |
| Onset / peak / duration | Onset 1 to 2 hours; duration up to 1.5 days. |
| Half-life / level | Biologic effect 18 to 36 hours. |
| Routes | PO (oral), Ophthalmic |
| High-alert (ISMP) | No |
| Black box warning | None |
| Antidote / reversal | None; taper. |
| Pregnancy / lactation | Use only if needed. |
Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.
Prednisolone (brand names Prelone, Orapred) — Anti-inflammatory, immunosuppressant; Systemic corticosteroid.
Identification
- Therapeutic class: Anti-inflammatory, immunosuppressant.
- Pharmacologic class: Systemic corticosteroid.
Pharmacology
- Mechanism of action: Same as prednisone; active form, useful when liver conversion is a concern (children, hepatic disease).
- Onset / peak / duration: Onset 1 to 2 hours; duration up to 1.5 days.
- Half-life / therapeutic level: Biologic effect 18 to 36 hours.
Clinical use
- Indications: Same as prednisone; common pediatric oral liquid; ophthalmic for eye inflammation.
- Usual dose, route, frequency: PO daily, liquid for children; OPH drops for eye conditions.
- Maximum dose / adjustments: Lowest effective dose; taper after prolonged use.
Safety
- Contraindications: Systemic fungal infection.
- Black box warning: None.
- Interactions: Same as prednisone.
- Pregnancy / lactation: Use only if needed.
- High-alert: No.
Adverse effects
- Common side effects: Same corticosteroid effects.
- Serious effects to report: Same as prednisone.
- Antidote / reversal: None; taper.
Nursing process
- Assessment before administration: Glucose, infection signs, weight.
- Interventions during therapy: With food; taper as ordered.
- Monitor: Glucose, blood pressure, growth in children.
- Evaluation / expected outcome: Reduced inflammation.
Patient teaching
- Patient teaching: Same as prednisone; measure liquid accurately.
- Notify provider if: Same as prednisone.
- Administration tips: With food; use an oral syringe for liquid.