Liraglutide
(Redirected from Saxenda)
| Drug monograph · NCLEX study reference | |
| Trade names | Victoza, Saxenda |
|---|---|
| Therapeutic class | Antidiabetic, weight management |
| Pharmacologic class | GLP-1 receptor agonist |
| Onset / peak / duration | Peak 8 to 12 hours; once-daily effect. |
| Half-life / level | Half-life about 13 hours; no routine level. |
| Routes | SubQ |
| High-alert (ISMP) | No |
| Black box warning | Yes (see Safety) |
| Antidote / reversal | None. |
| Pregnancy / lactation | Discontinue. |
Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.
Liraglutide (brand names Victoza, Saxenda) — Antidiabetic, weight management; GLP-1 receptor agonist.
Identification
- Therapeutic class: Antidiabetic, weight management.
- Pharmacologic class: GLP-1 receptor agonist.
Pharmacology
- Mechanism of action: Same as semaglutide; daily dosing.
- Onset / peak / duration: Peak 8 to 12 hours; once-daily effect.
- Half-life / therapeutic level: Half-life about 13 hours; no routine level.
Clinical use
- Indications: Type 2 diabetes (Victoza), weight management (Saxenda).
- Usual dose, route, frequency: SubQ daily, titrated (1.2 to 1.8 mg diabetes; up to 3 mg weight).
- Maximum dose / adjustments: Titrate weekly for tolerance.
Safety
- Contraindications: Medullary thyroid carcinoma history, MEN 2.
- Black box warning: Thyroid C-cell tumor risk (rodents).
- Interactions: Delayed gastric emptying, secretagogues and insulin.
- Pregnancy / lactation: Discontinue.
- High-alert: No.
Adverse effects
- Common side effects: Nausea, vomiting, diarrhea, decreased appetite.
- Serious effects to report: Pancreatitis, gallbladder disease.
- Antidote / reversal: None.
Nursing process
- Assessment before administration: Thyroid and pancreatitis history.
- Interventions during therapy: Daily injection; rotate sites.
- Monitor: A1c, weight, GI tolerance.
- Evaluation / expected outcome: Glycemic control and weight loss.
Patient teaching
- Patient teaching: Inject at the same time daily.
- Notify provider if: Severe abdominal pain, neck lump.
- Administration tips: SubQ; rotate sites.