View source for Rivastigmine and galantamine

<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''
</div>

'''Rivastigmine and galantamine''' (brand names Exelon, Razadyne) &mdash; Anti-Alzheimer; Cholinesterase inhibitors.

== Identification ==
* '''Therapeutic class:''' Anti-Alzheimer.
* '''Pharmacologic class:''' Cholinesterase inhibitors.

== Pharmacology ==
* '''Mechanism of action:''' Increase acetylcholine; rivastigmine also inhibits butyrylcholinesterase and has a patch form.
* '''Onset / peak / duration:''' Effect over weeks.
* '''Half-life / therapeutic level:''' Short to moderate; level not routine.

== Clinical use ==
* '''Indications:''' Alzheimer dementia; rivastigmine also for Parkinson dementia.
* '''Usual dose, route, frequency:''' Rivastigmine PO twice daily or transdermal daily; galantamine PO or ER.
* '''Maximum dose / adjustments:''' Titrate slowly; restart titration if therapy is interrupted.

== Safety ==
* '''Contraindications:''' Hypersensitivity.
* '''Black box warning:''' None.
* '''Interactions:''' Anticholinergics, beta blockers, NSAIDs.
* '''Pregnancy / lactation:''' Not typically used.
* '''High-alert:''' No.

== Adverse effects ==
* '''Common side effects:''' Nausea, vomiting, weight loss, dizziness.
* '''Serious effects to report:''' Bradycardia, GI bleeding, severe vomiting; rotate patch sites to prevent skin reactions.
* '''Antidote / reversal:''' Atropine for severe cholinergic effects.

== Nursing process ==
* '''Assessment before administration:''' Heart rate, weight, GI history.
* '''Interventions during therapy:''' Rotate patch sites; remove old patch before applying new.
* '''Monitor:''' Cognition, weight, heart rate.
* '''Evaluation / expected outcome:''' Slowed decline.

== Patient teaching ==
* '''Patient teaching:''' Apply only one patch; report severe nausea.
* '''Notify provider if:''' Fainting, slow heartbeat, persistent vomiting.
* '''Administration tips:''' With food; one patch at a time.

[[Category:Dementia, Migraine, Myasthenia, and Other Neuro Agents]]