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	<id>https://wiki.docmoates.com/index.php?action=history&amp;feed=atom&amp;title=Acetaminophen</id>
	<title>Acetaminophen - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wiki.docmoates.com/index.php?action=history&amp;feed=atom&amp;title=Acetaminophen"/>
	<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Acetaminophen&amp;action=history"/>
	<updated>2026-06-17T17:45:04Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wiki.docmoates.com/index.php?title=Acetaminophen&amp;diff=4795&amp;oldid=prev</id>
		<title>Docmoates: Add medication infobox (Drugbox) to monographs</title>
		<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Acetaminophen&amp;diff=4795&amp;oldid=prev"/>
		<updated>2026-06-17T16:09:12Z</updated>

		<summary type="html">&lt;p&gt;Add medication infobox (Drugbox) to monographs&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:09, 17 June 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{Drugbox&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| name = Acetaminophen&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| brand = Tylenol&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| therapeutic = Analgesic, antipyretic&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| pharmacologic = Para-aminophenol derivative&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| onset = PO onset 30 to 60 minutes; IV faster; duration 4 to 6 hours.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| halflife = Half-life about 2 hours; toxic level guides acetylcysteine dosing.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| routes = PO (oral), IV, Rectal&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| highalert = No&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| blackbox = None&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| antidote = Acetylcysteine for overdose.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| pregnancy = Preferred analgesic and antipyretic in pregnancy.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Docmoates</name></author>
	</entry>
	<entry>
		<id>https://wiki.docmoates.com/index.php?title=Acetaminophen&amp;diff=4039&amp;oldid=prev</id>
		<title>Docmoates: NCLEX nursing pharmacology monographs — batch import</title>
		<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Acetaminophen&amp;diff=4039&amp;oldid=prev"/>
		<updated>2026-06-17T14:05:00Z</updated>

		<summary type="html">&lt;p&gt;NCLEX nursing pharmacology monographs — batch import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;br /&gt;
&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Acetaminophen&amp;#039;&amp;#039;&amp;#039; (brand name Tylenol) &amp;amp;mdash; Analgesic, antipyretic; Para-aminophenol derivative.&lt;br /&gt;
&lt;br /&gt;
== Identification ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Therapeutic class:&amp;#039;&amp;#039;&amp;#039; Analgesic, antipyretic.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Pharmacologic class:&amp;#039;&amp;#039;&amp;#039; Para-aminophenol derivative.&lt;br /&gt;
&lt;br /&gt;
== Pharmacology ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Mechanism of action:&amp;#039;&amp;#039;&amp;#039; Acts centrally to reduce pain and fever; little anti-inflammatory effect and no antiplatelet or GI ulcer effect.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Onset / peak / duration:&amp;#039;&amp;#039;&amp;#039; PO onset 30 to 60 minutes; IV faster; duration 4 to 6 hours.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Half-life / therapeutic level:&amp;#039;&amp;#039;&amp;#039; Half-life about 2 hours; toxic level guides acetylcysteine dosing.&lt;br /&gt;
&lt;br /&gt;
== Clinical use ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Indications:&amp;#039;&amp;#039;&amp;#039; Mild to moderate pain, fever.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Usual dose, route, frequency:&amp;#039;&amp;#039;&amp;#039; 325 to 1,000 mg PO every 4 to 6 hours; IV and rectal available.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Maximum dose / adjustments:&amp;#039;&amp;#039;&amp;#039; Max 4 g/day (often capped at 3 g/day, lower with liver disease or alcohol use); count all combination products.&lt;br /&gt;
&lt;br /&gt;
== Safety ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Contraindications:&amp;#039;&amp;#039;&amp;#039; Severe hepatic impairment, hypersensitivity.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Black box warning:&amp;#039;&amp;#039;&amp;#039; None (the label warns of severe hepatotoxicity above recommended doses).&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Interactions:&amp;#039;&amp;#039;&amp;#039; Warfarin (raises INR at high regular doses), alcohol (hepatotoxicity, food/drink), other acetaminophen-containing products.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Pregnancy / lactation:&amp;#039;&amp;#039;&amp;#039; Preferred analgesic and antipyretic in pregnancy.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;High-alert:&amp;#039;&amp;#039;&amp;#039; No.&lt;br /&gt;
&lt;br /&gt;
== Adverse effects ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Common side effects:&amp;#039;&amp;#039;&amp;#039; Generally well tolerated.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Serious effects to report:&amp;#039;&amp;#039;&amp;#039; Hepatotoxicity (right upper abdominal pain, jaundice), rare severe skin reactions.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Antidote / reversal:&amp;#039;&amp;#039;&amp;#039; Acetylcysteine for overdose.&lt;br /&gt;
&lt;br /&gt;
== Nursing process ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Assessment before administration:&amp;#039;&amp;#039;&amp;#039; Pain or fever, total daily acetaminophen from all sources, liver function and alcohol use.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Interventions during therapy:&amp;#039;&amp;#039;&amp;#039; Add up every source to stay within the daily limit.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Monitor:&amp;#039;&amp;#039;&amp;#039; Pain and fever relief, LFTs with high or chronic use.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Evaluation / expected outcome:&amp;#039;&amp;#039;&amp;#039; Reduced pain or fever.&lt;br /&gt;
&lt;br /&gt;
== Patient teaching ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Patient teaching:&amp;#039;&amp;#039;&amp;#039; Do not exceed the daily limit; check combination cold and pain products for hidden acetaminophen; limit alcohol.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Notify provider if:&amp;#039;&amp;#039;&amp;#039; Right upper abdominal pain, yellowing of skin, dark urine.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Administration tips:&amp;#039;&amp;#039;&amp;#039; Track total daily dose across all products.&lt;br /&gt;
&lt;br /&gt;
[[Category:Nonopioid Analgesic]]&lt;/div&gt;</summary>
		<author><name>Docmoates</name></author>
	</entry>
</feed>