Docmoates: Add medication infobox (Drugbox) to monographs

2026-06-17T16:09:18Z

Add medication infobox (Drugbox) to monographs

← Older revision		Revision as of 16:09, 17 June 2026
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			{{Drugbox
			\| name = Cephalosporins
			\| therapeutic = Antibacterial
			\| pharmacologic = Beta-lactam (cephalosporins)
			\| onset = Rapid; dosing interval varies (ceftriaxone often once daily).
			\| halflife = Mostly short except ceftriaxone (longer); no routine level.
			\| routes = PO (oral), IV, IM
			\| highalert = No
			\| blackbox = None
			\| antidote = Epinephrine and supportive care for anaphylaxis.
			\| pregnancy = Generally considered safe.
			}}

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	''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''		''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''

Docmoates: NCLEX nursing pharmacology monographs — batch import

2026-06-17T14:05:28Z

NCLEX nursing pharmacology monographs — batch import

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<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''
</div>

'''Cephalosporins''' — Antibacterial; Beta-lactam (cephalosporins).

== Identification ==
* '''Therapeutic class:''' Antibacterial.
* '''Pharmacologic class:''' Beta-lactam (cephalosporins).

== Pharmacology ==
* '''Mechanism of action:''' Inhibit cell wall synthesis (bactericidal); higher generations gain gram-negative coverage.
* '''Onset / peak / duration:''' Rapid; dosing interval varies (ceftriaxone often once daily).
* '''Half-life / therapeutic level:''' Mostly short except ceftriaxone (longer); no routine level.

== Clinical use ==
* '''Indications:''' Skin, respiratory, urinary infections (cephalexin), surgical prophylaxis (cefazolin), gonorrhea and serious infections (ceftriaxone), hospital and pseudomonal infections (cefepime, ceftazidime).
* '''Usual dose, route, frequency:''' Cephalexin PO; ceftriaxone IV or IM once or twice daily; cefepime IV every 8 to 12 hours.
* '''Maximum dose / adjustments:''' Reduce in renal impairment (cefepime neurotoxicity risk if not adjusted); ceftriaxone caution in neonates.

== Safety ==
* '''Contraindications:''' Cephalosporin hypersensitivity; ceftriaxone with calcium-containing IV in neonates; severe penicillin allergy (cross-reactivity, low but present).
* '''Black box warning:''' None.
* '''Interactions:''' Probenecid, warfarin, alcohol (disulfiram-like reaction with some, food/drink), nephrotoxic drugs.
* '''Pregnancy / lactation:''' Generally considered safe.
* '''High-alert:''' No.

== Adverse effects ==
* '''Common side effects:''' Diarrhea, rash, GI upset.
* '''Serious effects to report:''' Anaphylaxis, C. difficile colitis, cefepime neurotoxicity (confusion, seizures), severe rash.
* '''Antidote / reversal:''' Epinephrine and supportive care for anaphylaxis.

== Nursing process ==
* '''Assessment before administration:''' Allergy history (including penicillin), cultures, renal function.
* '''Interventions during therapy:''' Do not mix ceftriaxone with calcium-containing solutions in neonates; observe for reaction.
* '''Monitor:''' Allergy signs, renal function, neuro status (cefepime), infection resolution.
* '''Evaluation / expected outcome:''' Resolution of infection.

== Patient teaching ==
* '''Patient teaching:''' Finish the course; avoid alcohol with certain cephalosporins; report rash.
* '''Notify provider if:''' Rash or hives, breathing difficulty, severe diarrhea, confusion.
* '''Administration tips:''' Take oral forms on schedule; cefdinir absorption reduced by iron and antacids (separate by 2 hours).

[[Category:Cephalosporins]]

Cephalosporins - Revision history

Docmoates: Add medication infobox (Drugbox) to monographs

Docmoates: NCLEX nursing pharmacology monographs — batch import