https://wiki.docmoates.com/index.php?action=history&feed=atom&title=Clonidine 2026-06-17T15:49:57Z Revision history for this page on the wiki MediaWiki 1.42.4 https://wiki.docmoates.com/index.php?title=Clonidine&diff=3964&oldid=prev 2026-06-17T13:37:14Z

<p>NCLEX nursing pharmacology monographs — batch import</p> <p><b>New page</b></p><div>&lt;div style=&quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&quot;&gt;<br /> &#039;&#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &#039;&#039;&#039;must be verified against current manufacturer labeling before clinical use&#039;&#039;&#039;. This is educational content, not prescribing guidance.&#039;&#039;<br /> &lt;/div&gt;<br /> <br /> &#039;&#039;&#039;Clonidine&#039;&#039;&#039; (brand name Catapres) &amp;mdash; Antihypertensive; Central alpha-2 adrenergic agonist.<br /> <br /> == Identification ==<br /> * &#039;&#039;&#039;Therapeutic class:&#039;&#039;&#039; Antihypertensive.<br /> * &#039;&#039;&#039;Pharmacologic class:&#039;&#039;&#039; Central alpha-2 adrenergic agonist.<br /> <br /> == Pharmacology ==<br /> * &#039;&#039;&#039;Mechanism of action:&#039;&#039;&#039; Stimulates central alpha-2 receptors, reducing sympathetic outflow and lowering blood pressure and heart rate.<br /> * &#039;&#039;&#039;Onset / peak / duration:&#039;&#039;&#039; PO onset 30 to 60 minutes; patch provides 7-day effect.<br /> * &#039;&#039;&#039;Half-life / therapeutic level:&#039;&#039;&#039; Half-life 12 to 16 hours; no routine level.<br /> <br /> == Clinical use ==<br /> * &#039;&#039;&#039;Indications:&#039;&#039;&#039; Hypertension, ADHD, opioid withdrawal, tic disorders.<br /> * &#039;&#039;&#039;Usual dose, route, frequency:&#039;&#039;&#039; 0.1 to 0.3 mg PO twice daily; transdermal patch weekly.<br /> * &#039;&#039;&#039;Maximum dose / adjustments:&#039;&#039;&#039; Up to about 2.4 mg/day; taper to discontinue.<br /> <br /> == Safety ==<br /> * &#039;&#039;&#039;Contraindications:&#039;&#039;&#039; Hypersensitivity; caution with bradycardia.<br /> * &#039;&#039;&#039;Black box warning:&#039;&#039;&#039; None (the epidural injectable form carries one, but the oral and patch forms do not).<br /> * &#039;&#039;&#039;Interactions:&#039;&#039;&#039; Beta blockers (rebound hypertension risk if stopped together), central nervous system depressants, tricyclic antidepressants (reduced effect).<br /> * &#039;&#039;&#039;Pregnancy / lactation:&#039;&#039;&#039; Use only if clearly needed.<br /> * &#039;&#039;&#039;High-alert:&#039;&#039;&#039; No.<br /> <br /> == Adverse effects ==<br /> * &#039;&#039;&#039;Common side effects:&#039;&#039;&#039; Drowsiness, dry mouth, dizziness, constipation, bradycardia.<br /> * &#039;&#039;&#039;Serious effects to report:&#039;&#039;&#039; Rebound hypertension on abrupt withdrawal, severe bradycardia.<br /> * &#039;&#039;&#039;Antidote / reversal:&#039;&#039;&#039; Supportive care; reintroduce drug for rebound hypertension.<br /> <br /> == Nursing process ==<br /> * &#039;&#039;&#039;Assessment before administration:&#039;&#039;&#039; Blood pressure, heart rate.<br /> * &#039;&#039;&#039;Interventions during therapy:&#039;&#039;&#039; Never stop abruptly; rotate patch sites.<br /> * &#039;&#039;&#039;Monitor:&#039;&#039;&#039; Blood pressure, heart rate.<br /> * &#039;&#039;&#039;Evaluation / expected outcome:&#039;&#039;&#039; Controlled blood pressure.<br /> <br /> == Patient teaching ==<br /> * &#039;&#039;&#039;Patient teaching:&#039;&#039;&#039; Do not stop suddenly; sedation and dry mouth are common.<br /> * &#039;&#039;&#039;Notify provider if:&#039;&#039;&#039; Sudden severe headache or blood pressure spike, very slow heartbeat.<br /> * &#039;&#039;&#039;Administration tips:&#039;&#039;&#039; Apply patch to clean, hairless skin; rotate sites; bedtime oral dose reduces daytime sedation.<br /> <br /> [[Category:Other Antihypertensives and Vasodilators]]</div>

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