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	<id>https://wiki.docmoates.com/index.php?action=history&amp;feed=atom&amp;title=Inhaled_and_local_anesthetics</id>
	<title>Inhaled and local anesthetics - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wiki.docmoates.com/index.php?action=history&amp;feed=atom&amp;title=Inhaled_and_local_anesthetics"/>
	<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Inhaled_and_local_anesthetics&amp;action=history"/>
	<updated>2026-06-17T19:28:44Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.42.4</generator>
	<entry>
		<id>https://wiki.docmoates.com/index.php?title=Inhaled_and_local_anesthetics&amp;diff=4894&amp;oldid=prev</id>
		<title>Docmoates: Add medication infobox (Drugbox) to monographs</title>
		<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Inhaled_and_local_anesthetics&amp;diff=4894&amp;oldid=prev"/>
		<updated>2026-06-17T16:09:27Z</updated>

		<summary type="html">&lt;p&gt;Add medication infobox (Drugbox) to monographs&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:09, 17 June 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{Drugbox&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| name = Inhaled and local anesthetics&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| therapeutic = Anesthetic&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| pharmacologic = Volatile inhaled anesthetics; amide local anesthetics&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| onset = Inhaled rapid and titratable; local anesthetics minutes to onset with duration by agent (bupivacaine long).&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| halflife = Variable; no routine level.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| routes = Transdermal, Inhaled, Topical&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| highalert = No&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| blackbox = None&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| antidote = Dantrolene for malignant hyperthermia; lipid emulsion for local anesthetic systemic toxicity.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| pregnancy = Used in anesthesia care as needed.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Docmoates</name></author>
	</entry>
	<entry>
		<id>https://wiki.docmoates.com/index.php?title=Inhaled_and_local_anesthetics&amp;diff=4408&amp;oldid=prev</id>
		<title>Docmoates: NCLEX nursing pharmacology monographs — batch import</title>
		<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Inhaled_and_local_anesthetics&amp;diff=4408&amp;oldid=prev"/>
		<updated>2026-06-17T14:05:58Z</updated>

		<summary type="html">&lt;p&gt;NCLEX nursing pharmacology monographs — batch import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;br /&gt;
&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Inhaled and local anesthetics&amp;#039;&amp;#039;&amp;#039; &amp;amp;mdash; Anesthetic; Volatile inhaled anesthetics; amide local anesthetics.&lt;br /&gt;
&lt;br /&gt;
== Identification ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Therapeutic class:&amp;#039;&amp;#039;&amp;#039; Anesthetic.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Pharmacologic class:&amp;#039;&amp;#039;&amp;#039; Volatile inhaled anesthetics; amide local anesthetics.&lt;br /&gt;
&lt;br /&gt;
== Pharmacology ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Mechanism of action:&amp;#039;&amp;#039;&amp;#039; Inhaled agents produce general anesthesia through central depression; local anesthetics block sodium channels to stop nerve conduction in a region.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Onset / peak / duration:&amp;#039;&amp;#039;&amp;#039; Inhaled rapid and titratable; local anesthetics minutes to onset with duration by agent (bupivacaine long).&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Half-life / therapeutic level:&amp;#039;&amp;#039;&amp;#039; Variable; no routine level.&lt;br /&gt;
&lt;br /&gt;
== Clinical use ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Indications:&amp;#039;&amp;#039;&amp;#039; General anesthesia (inhaled), local and regional anesthesia and nerve blocks (local), lidocaine also as an antiarrhythmic and topical.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Usual dose, route, frequency:&amp;#039;&amp;#039;&amp;#039; Inhaled by anesthesia provider; local by injection, topical, or patch.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Maximum dose / adjustments:&amp;#039;&amp;#039;&amp;#039; Respect maximum local anesthetic doses (especially bupivacaine, which is cardiotoxic); epinephrine-containing solutions not used in end-arterial areas (fingers, toes, nose, ears).&lt;br /&gt;
&lt;br /&gt;
== Safety ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Contraindications:&amp;#039;&amp;#039;&amp;#039; Malignant hyperthermia history (volatile agents are triggers), amide anesthetic allergy.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Black box warning:&amp;#039;&amp;#039;&amp;#039; None for these prototypes.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Interactions:&amp;#039;&amp;#039;&amp;#039; Other CNS depressants; local anesthetics with antiarrhythmics (additive cardiac effects).&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Pregnancy / lactation:&amp;#039;&amp;#039;&amp;#039; Used in anesthesia care as needed.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;High-alert:&amp;#039;&amp;#039;&amp;#039; No.&lt;br /&gt;
&lt;br /&gt;
== Adverse effects ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Common side effects:&amp;#039;&amp;#039;&amp;#039; Nausea after general anesthesia; local numbness and tingling.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Serious effects to report:&amp;#039;&amp;#039;&amp;#039; Malignant hyperthermia (volatile agents), local anesthetic systemic toxicity (CNS excitation then seizures, cardiac toxicity), bupivacaine cardiotoxicity.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Antidote / reversal:&amp;#039;&amp;#039;&amp;#039; Dantrolene for malignant hyperthermia; lipid emulsion for local anesthetic systemic toxicity.&lt;br /&gt;
&lt;br /&gt;
== Nursing process ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Assessment before administration:&amp;#039;&amp;#039;&amp;#039; Malignant hyperthermia history, allergies, vital signs.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Interventions during therapy:&amp;#039;&amp;#039;&amp;#039; Continuous monitoring; have dantrolene available in surgical areas; aspirate before injecting local anesthetic.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Monitor:&amp;#039;&amp;#039;&amp;#039; Temperature and rigidity (malignant hyperthermia), CNS and cardiac signs.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Evaluation / expected outcome:&amp;#039;&amp;#039;&amp;#039; Adequate anesthesia.&lt;br /&gt;
&lt;br /&gt;
== Patient teaching ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Patient teaching:&amp;#039;&amp;#039;&amp;#039; Report any family history of anesthesia reactions before surgery.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Notify provider if:&amp;#039;&amp;#039;&amp;#039; Not applicable (monitored setting).&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Administration tips:&amp;#039;&amp;#039;&amp;#039; Monitored settings; respect local anesthetic dose limits.&lt;br /&gt;
&lt;br /&gt;
[[Category:Anesthesia Agents]]&lt;/div&gt;</summary>
		<author><name>Docmoates</name></author>
	</entry>
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