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	<id>https://wiki.docmoates.com/index.php?action=history&amp;feed=atom&amp;title=Lactulose</id>
	<title>Lactulose - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wiki.docmoates.com/index.php?action=history&amp;feed=atom&amp;title=Lactulose"/>
	<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Lactulose&amp;action=history"/>
	<updated>2026-06-17T18:10:47Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.42.4</generator>
	<entry>
		<id>https://wiki.docmoates.com/index.php?title=Lactulose&amp;diff=4908&amp;oldid=prev</id>
		<title>Docmoates: Add medication infobox (Drugbox) to monographs</title>
		<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Lactulose&amp;diff=4908&amp;oldid=prev"/>
		<updated>2026-06-17T16:09:29Z</updated>

		<summary type="html">&lt;p&gt;Add medication infobox (Drugbox) to monographs&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:09, 17 June 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{Drugbox&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| name = Lactulose&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| brand = Enulose&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| therapeutic = Laxative, ammonia-reducing agent&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| pharmacologic = Osmotic laxative (nonabsorbable sugar)&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| onset = Laxative onset 24 to 48 hours; faster in hepatic encephalopathy.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| halflife = Minimal absorption.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| routes = PO (oral), Rectal&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| highalert = No&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| blackbox = None&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| antidote = Not applicable.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;| pregnancy = Used when needed.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Docmoates</name></author>
	</entry>
	<entry>
		<id>https://wiki.docmoates.com/index.php?title=Lactulose&amp;diff=4436&amp;oldid=prev</id>
		<title>Docmoates: NCLEX nursing pharmacology monographs — batch import</title>
		<link rel="alternate" type="text/html" href="https://wiki.docmoates.com/index.php?title=Lactulose&amp;diff=4436&amp;oldid=prev"/>
		<updated>2026-06-17T14:06:02Z</updated>

		<summary type="html">&lt;p&gt;NCLEX nursing pharmacology monographs — batch import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;lt;div style=&amp;quot;border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;&amp;quot;&amp;gt;&lt;br /&gt;
&amp;#039;&amp;#039;Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and &amp;#039;&amp;#039;&amp;#039;must be verified against current manufacturer labeling before clinical use&amp;#039;&amp;#039;&amp;#039;. This is educational content, not prescribing guidance.&amp;#039;&amp;#039;&lt;br /&gt;
&amp;lt;/div&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Lactulose&amp;#039;&amp;#039;&amp;#039; (brand name Enulose) &amp;amp;mdash; Laxative, ammonia-reducing agent; Osmotic laxative (nonabsorbable sugar).&lt;br /&gt;
&lt;br /&gt;
== Identification ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Therapeutic class:&amp;#039;&amp;#039;&amp;#039; Laxative, ammonia-reducing agent.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Pharmacologic class:&amp;#039;&amp;#039;&amp;#039; Osmotic laxative (nonabsorbable sugar).&lt;br /&gt;
&lt;br /&gt;
== Pharmacology ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Mechanism of action:&amp;#039;&amp;#039;&amp;#039; Draws water into the bowel and traps ammonia for elimination.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Onset / peak / duration:&amp;#039;&amp;#039;&amp;#039; Laxative onset 24 to 48 hours; faster in hepatic encephalopathy.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Half-life / therapeutic level:&amp;#039;&amp;#039;&amp;#039; Minimal absorption.&lt;br /&gt;
&lt;br /&gt;
== Clinical use ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Indications:&amp;#039;&amp;#039;&amp;#039; Constipation, hepatic encephalopathy.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Usual dose, route, frequency:&amp;#039;&amp;#039;&amp;#039; 15 to 30 mL PO daily for constipation; higher and titrated to stools for encephalopathy; rectal in acute cases.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Maximum dose / adjustments:&amp;#039;&amp;#039;&amp;#039; Titrate to 2 to 3 soft stools per day for encephalopathy.&lt;br /&gt;
&lt;br /&gt;
== Safety ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Contraindications:&amp;#039;&amp;#039;&amp;#039; Galactosemia, low-galactose diet.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Black box warning:&amp;#039;&amp;#039;&amp;#039; None.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Interactions:&amp;#039;&amp;#039;&amp;#039; Other laxatives, antibiotics (may reduce effect).&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Pregnancy / lactation:&amp;#039;&amp;#039;&amp;#039; Used when needed.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;High-alert:&amp;#039;&amp;#039;&amp;#039; No.&lt;br /&gt;
&lt;br /&gt;
== Adverse effects ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Common side effects:&amp;#039;&amp;#039;&amp;#039; Bloating, flatulence, cramping, sweet taste.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Serious effects to report:&amp;#039;&amp;#039;&amp;#039; Excessive diarrhea with dehydration and electrolyte loss.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Antidote / reversal:&amp;#039;&amp;#039;&amp;#039; Not applicable.&lt;br /&gt;
&lt;br /&gt;
== Nursing process ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Assessment before administration:&amp;#039;&amp;#039;&amp;#039; Bowel pattern, ammonia and mental status for encephalopathy.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Interventions during therapy:&amp;#039;&amp;#039;&amp;#039; Titrate to stool goal; can mix in juice for taste.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Monitor:&amp;#039;&amp;#039;&amp;#039; Stool frequency, ammonia, mental status, electrolytes.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Evaluation / expected outcome:&amp;#039;&amp;#039;&amp;#039; Regular stools or improved mental status.&lt;br /&gt;
&lt;br /&gt;
== Patient teaching ==&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Patient teaching:&amp;#039;&amp;#039;&amp;#039; For encephalopathy, the goal is several soft stools daily.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Notify provider if:&amp;#039;&amp;#039;&amp;#039; Severe diarrhea, worsening confusion.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Administration tips:&amp;#039;&amp;#039;&amp;#039; Mix in juice or water; titrate as directed.&lt;br /&gt;
&lt;br /&gt;
[[Category:Laxatives, Antidiarrheals, and Other GI Agents]]&lt;/div&gt;</summary>
		<author><name>Docmoates</name></author>
	</entry>
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