Docmoates: Add medication infobox (Drugbox) to monographs

2026-06-17T16:09:32Z

Add medication infobox (Drugbox) to monographs

← Older revision		Revision as of 16:09, 17 June 2026
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			{{Drugbox
			\| name = Macrolides
			\| therapeutic = Antibacterial
			\| pharmacologic = Macrolide
			\| onset = Azithromycin has a long tissue half-life (short courses, once daily).
			\| halflife = Azithromycin about 68 hours; no routine level.
			\| routes = PO (oral), IV
			\| highalert = No
			\| blackbox = None
			\| antidote = Supportive care.
			\| pregnancy = Azithromycin commonly used when needed.
			}}

	<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">		<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
	''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''		''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''

Docmoates: NCLEX nursing pharmacology monographs — batch import

2026-06-17T14:06:09Z

NCLEX nursing pharmacology monographs — batch import

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<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''
</div>

'''Macrolides''' — Antibacterial; Macrolide.

== Identification ==
* '''Therapeutic class:''' Antibacterial.
* '''Pharmacologic class:''' Macrolide.

== Pharmacology ==
* '''Mechanism of action:''' Bind the 50S ribosomal subunit to inhibit protein synthesis (bacteriostatic).
* '''Onset / peak / duration:''' Azithromycin has a long tissue half-life (short courses, once daily).
* '''Half-life / therapeutic level:''' Azithromycin about 68 hours; no routine level.

== Clinical use ==
* '''Indications:''' Respiratory infections, atypical pneumonia, pertussis, sexually transmitted infections, H. pylori (clarithromycin).
* '''Usual dose, route, frequency:''' Azithromycin PO once daily (often a 5-day pack) or IV; erythromycin several times daily.
* '''Maximum dose / adjustments:''' Caution in hepatic impairment and with QT risk.

== Safety ==
* '''Contraindications:''' Hypersensitivity, history of cholestatic jaundice with macrolides, certain QT-prolonging drug combinations.
* '''Black box warning:''' None.
* '''Interactions:''' QT-prolonging drugs, warfarin, statins (clarithromycin and erythromycin via CYP3A4, myopathy), digoxin; food affects some.
* '''Pregnancy / lactation:''' Azithromycin commonly used when needed.
* '''High-alert:''' No.

== Adverse effects ==
* '''Common side effects:''' GI upset, diarrhea, abdominal cramping (erythromycin notably), taste changes.
* '''Serious effects to report:''' QT prolongation and arrhythmia, hepatotoxicity, C. difficile colitis.
* '''Antidote / reversal:''' Supportive care.

== Nursing process ==
* '''Assessment before administration:''' Allergy, cardiac and QT history, interacting drugs, hepatic function.
* '''Interventions during therapy:''' Review QT-prolonging and CYP3A4 drugs.
* '''Monitor:''' Cardiac status if at risk, LFTs, infection resolution.
* '''Evaluation / expected outcome:''' Resolution of infection.

== Patient teaching ==
* '''Patient teaching:''' Finish the course; report palpitations; take erythromycin with food for GI upset.
* '''Notify provider if:''' Palpitations, fainting, yellowing of skin, severe diarrhea.
* '''Administration tips:''' Azithromycin with or without food; separate from aluminum and magnesium antacids.

[[Category:Macrolides]]

Macrolides - Revision history

Docmoates: Add medication infobox (Drugbox) to monographs

Docmoates: NCLEX nursing pharmacology monographs — batch import