Bumetanide
| Drug monograph · NCLEX study reference | |
| Trade names | Bumex |
|---|---|
| Therapeutic class | Diuretic |
| Pharmacologic class | Loop diuretic |
| Onset / peak / duration | PO onset 30 to 60 minutes; IV within minutes; duration 4 to 6 hours. |
| Half-life / level | Half-life 1 to 1.5 hours; no routine level. |
| Routes | PO (oral), IV |
| High-alert (ISMP) | No |
| Black box warning | Yes (see Safety) |
| Antidote / reversal | None; supportive. |
| Pregnancy / lactation | Use only if clearly needed. |
Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.
Bumetanide (brand name Bumex) — Diuretic; Loop diuretic.
Identification
- Therapeutic class: Diuretic.
- Pharmacologic class: Loop diuretic.
Pharmacology
- Mechanism of action: Same loop mechanism as furosemide; more potent per milligram (1 mg roughly equals 40 mg furosemide).
- Onset / peak / duration: PO onset 30 to 60 minutes; IV within minutes; duration 4 to 6 hours.
- Half-life / therapeutic level: Half-life 1 to 1.5 hours; no routine level.
Clinical use
- Indications: Edema, especially when furosemide is inadequate.
- Usual dose, route, frequency: 0.5 to 2 mg PO or IV once or twice daily.
- Maximum dose / adjustments: Max about 10 mg/day; close electrolyte monitoring.
Safety
- Contraindications: Anuria, severe electrolyte depletion.
- Black box warning: Profound diuresis with fluid and electrolyte loss; individualize and monitor.
- Interactions: Same as furosemide.
- Pregnancy / lactation: Use only if clearly needed.
- High-alert: No.
Adverse effects
- Common side effects: Hypokalemia, dizziness, increased urination.
- Serious effects to report: Severe dehydration, ototoxicity, electrolyte loss.
- Antidote / reversal: None; supportive.
Nursing process
- Assessment before administration: Weight, electrolytes, renal function, blood pressure.
- Interventions during therapy: Morning dosing; monitor potassium.
- Monitor: Electrolytes, weight, intake and output, renal function.
- Evaluation / expected outcome: Reduced edema.
Patient teaching
- Patient teaching: Same as furosemide.
- Notify provider if: Cramps, hearing changes, severe dizziness.
- Administration tips: Morning dosing.