Dexlansoprazole
Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.
Dexlansoprazole (brand name Dexilant) — Antiulcer, antisecretory; Proton pump inhibitor.
Identification
- Therapeutic class: Antiulcer, antisecretory.
- Pharmacologic class: Proton pump inhibitor.
Pharmacology
- Mechanism of action: Dual delayed-release proton pump blockade providing extended acid control.
- Onset / peak / duration: Two release peaks; sustained effect.
- Half-life / therapeutic level: Half-life 1 to 2 hours with long effect.
Clinical use
- Indications: GERD, erosive esophagitis.
- Usual dose, route, frequency: 30 to 60 mg PO once daily, any time.
- Maximum dose / adjustments: Reduce in moderate hepatic impairment.
Safety
- Contraindications: Hypersensitivity.
- Black box warning: None.
- Interactions: Same PPI interactions.
- Pregnancy / lactation: Use if needed.
- High-alert: No.
Adverse effects
- Common side effects: Diarrhea, headache, nausea.
- Serious effects to report: C. difficile, hypomagnesemia, interstitial nephritis.
- Antidote / reversal: Not applicable.
Nursing process
- Assessment before administration: Symptoms, magnesium with long use.
- Interventions during therapy: Can be taken without regard to meals.
- Monitor: Symptom relief, magnesium with long use.
- Evaluation / expected outcome: Reduced reflux.
Patient teaching
- Patient teaching: May open capsule onto applesauce; do not chew granules.
- Notify provider if: Persistent diarrhea, cramps.
- Administration tips: Any time of day; swallow whole or sprinkle.