Senna

Senna

Drug monograph · NCLEX study reference
Trade names	Senokot
Therapeutic class	Laxative
Pharmacologic class	Stimulant laxative
Onset / peak / duration	Onset 6 to 12 hours.
Half-life / level	Minimal absorption.
Routes	PO (oral)
High-alert (ISMP)	No
Black box warning	None
Antidote / reversal	Not applicable.
Pregnancy / lactation	Commonly used.

Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.

Senna (brand name Senokot) — Laxative; Stimulant laxative.

Identification

• Therapeutic class: Laxative.
• Pharmacologic class: Stimulant laxative.

Pharmacology

• Mechanism of action: Stimulates intestinal motility.
• Onset / peak / duration: Onset 6 to 12 hours.
• Half-life / therapeutic level: Minimal absorption.

Clinical use

• Indications: Constipation, opioid-induced constipation (with a softener).
• Usual dose, route, frequency: 8.6 to 17.2 mg PO at bedtime.
• Maximum dose / adjustments: Short-term use; chronic use can cause dependence.

Safety

• Contraindications: Bowel obstruction, acute abdomen.
• Black box warning: None.
• Interactions: Minimal.
• Pregnancy / lactation: Commonly used.
• High-alert: No.

Adverse effects

• Common side effects: Cramping, urine discoloration.
• Serious effects to report: Severe cramping, no bowel movement with pain.
• Antidote / reversal: Not applicable.

Nursing process

• Assessment before administration: Bowel pattern.
• Interventions during therapy: Pair with a softener for opioid constipation.
• Monitor: Bowel movements.
• Evaluation / expected outcome: Bowel movement overnight.

Patient teaching

• Patient teaching: Take at bedtime for a morning result.
• Notify provider if: No relief, severe cramping.
• Administration tips: Bedtime dosing.