Fluticasone-umeclidinium-vilanterol (Trelegy): Difference between revisions

From Doc Moates Wiki
Jump to navigation Jump to search
NCLEX nursing pharmacology monographs — batch import
 
Add medication infobox (Drugbox) to monographs
 
Line 1: Line 1:
{{Drugbox
| name = Fluticasone-umeclidinium-vilanterol (Trelegy)
| brand = Trelegy
| therapeutic = COPD and asthma controller
| pharmacologic = Inhaled corticosteroid plus LAMA plus LABA (triple therapy)
| onset = 24-hour effect.
| halflife = No routine level.
| routes = Inhaled
| highalert = No
| blackbox = None
| antidote = Supportive care.
| pregnancy = Use if needed.
}}
<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''

Latest revision as of 16:09, 17 June 2026

Fluticasone-umeclidinium-vilanterol (Trelegy)
Drug monograph · NCLEX study reference
Trade namesTrelegy
Therapeutic classCOPD and asthma controller
Pharmacologic classInhaled corticosteroid plus LAMA plus LABA (triple therapy)
Onset / peak / duration24-hour effect.
Half-life / levelNo routine level.
RoutesInhaled
High-alert (ISMP)No
Black box warningNone
Antidote / reversalSupportive care.
Pregnancy / lactationUse if needed.

Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.

Fluticasone-umeclidinium-vilanterol (Trelegy) (brand name Trelegy) — COPD and asthma controller; Inhaled corticosteroid plus LAMA plus LABA (triple therapy).

Identification

  • Therapeutic class: COPD and asthma controller.
  • Pharmacologic class: Inhaled corticosteroid plus LAMA plus LABA (triple therapy).

Pharmacology

  • Mechanism of action: Combines anti-inflammatory, anticholinergic, and beta-agonist bronchodilation.
  • Onset / peak / duration: 24-hour effect.
  • Half-life / therapeutic level: No routine level.

Clinical use

  • Indications: COPD and asthma maintenance.
  • Usual dose, route, frequency: Inhaled once daily.
  • Maximum dose / adjustments: Once daily only.

Safety

  • Contraindications: Acute bronchospasm primary treatment.
  • Black box warning: None.
  • Interactions: CYP3A4 inhibitors, beta blockers, other anticholinergics, QT-prolonging drugs.
  • Pregnancy / lactation: Use if needed.
  • High-alert: No.

Adverse effects

  • Common side effects: Thrush, dry mouth, headache, upper respiratory symptoms.
  • Serious effects to report: Paradoxical bronchospasm, glaucoma, urinary retention.
  • Antidote / reversal: Supportive care.

Nursing process

  • Assessment before administration: Respiratory status, glaucoma and prostate history, oral mucosa.
  • Interventions during therapy: Once daily; rinse mouth; keep a rescue inhaler.
  • Monitor: Symptom control.
  • Evaluation / expected outcome: Improved control.

Patient teaching

  • Patient teaching: Once-daily controller; rinse after; not a rescue.
  • Notify provider if: Eye or urinary symptoms, worsening breathing.
  • Administration tips: Same time daily; rinse mouth.