Benazepril: Difference between revisions

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NCLEX nursing pharmacology monographs — batch import
 
Add medication infobox (Drugbox) to monographs
 
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{{Drugbox
| name = Benazepril
| brand = Lotensin
| therapeutic = Antihypertensive
| pharmacologic = ACE inhibitor
| onset = Onset about 1 hour; peak 2 to 4 hours; duration about 24 hours.
| halflife = Half-life about 10 to 11 hours; no routine level.
| routes = PO (oral)
| highalert = No
| blackbox = <span style="color:#b00020;">'''Yes'''</span> (see Safety)
| antidote = None specific.
| pregnancy = Contraindicated.
}}
<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
<div style="border-left:4px solid #3f6f5b;background:#f3f6f4;padding:8px 12px;margin-bottom:12px;font-size:0.95em;">
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''
''Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and '''must be verified against current manufacturer labeling before clinical use'''. This is educational content, not prescribing guidance.''

Latest revision as of 16:09, 17 June 2026

Benazepril
Drug monograph · NCLEX study reference
Trade namesLotensin
Therapeutic classAntihypertensive
Pharmacologic classACE inhibitor
Onset / peak / durationOnset about 1 hour; peak 2 to 4 hours; duration about 24 hours.
Half-life / levelHalf-life about 10 to 11 hours; no routine level.
RoutesPO (oral)
High-alert (ISMP)No
Black box warningYes (see Safety)
Antidote / reversalNone specific.
Pregnancy / lactationContraindicated.

Nursing pharmacology study reference (NCLEX-style monograph). Numeric values are standard teaching ranges for study and must be verified against current manufacturer labeling before clinical use. This is educational content, not prescribing guidance.

Benazepril (brand name Lotensin) — Antihypertensive; ACE inhibitor.

Identification

  • Therapeutic class: Antihypertensive.
  • Pharmacologic class: ACE inhibitor.

Pharmacology

  • Mechanism of action: Same ACE inhibition.
  • Onset / peak / duration: Onset about 1 hour; peak 2 to 4 hours; duration about 24 hours.
  • Half-life / therapeutic level: Half-life about 10 to 11 hours; no routine level.

Clinical use

  • Indications: Hypertension, often in combination products.
  • Usual dose, route, frequency: 10 to 40 mg PO daily in 1 to 2 doses.
  • Maximum dose / adjustments: Max 80 mg/day; reduce in renal impairment.

Safety

  • Contraindications: Angioedema history, pregnancy.
  • Black box warning: Fetal toxicity.
  • Interactions: Class ACE interactions.
  • Pregnancy / lactation: Contraindicated.
  • High-alert: No.

Adverse effects

  • Common side effects: Cough, dizziness, headache.
  • Serious effects to report: Angioedema, hyperkalemia, renal impairment.
  • Antidote / reversal: None specific.

Nursing process

  • Assessment before administration: Blood pressure, renal function, potassium, pregnancy status.
  • Interventions during therapy: Monitor for hypotension.
  • Monitor: Blood pressure, potassium, renal function.
  • Evaluation / expected outcome: Blood pressure at goal.

Patient teaching

  • Patient teaching: Same as other ACE inhibitors.
  • Notify provider if: Swelling, breathing difficulty, persistent cough.
  • Administration tips: Consistent daily timing.